ABSTRACT
Background: Endothelial dysfunction is associated to erectile dysfunction. This last condition can even be considered as a cardiovascular risk factor. Aim: To determine the frequency of erectile dysfunction among hospitalized patients with and without acute coronary syndromes. Material and Methods: Prospective cross sectional study in which all male patients, aged 40 to 70 years admitted to the emergency room or medicine service of a general hospital in a period of two months, were included. Those with acute coronary syndromes were considered as cases and those without, as controls. The international erectile dysfunction index questionnaire (IIEF-5) was applied to all. Results: Forty four patients with acute coronary syndrome aged 57 +/- 8 years and 46 controls aged 56 +/- 9 years were included. Erectile dysfunction was present in 34 (77 percent) cases and 20 (44 percent) controls (p < 0.01). The odds ratio of having erectile dysfunction among coronary patients was 4.4 (95 percent confidence intervals 1.6-12.3). Conclusions: There was a higher frequency of erectile dysfunction among patients with acute coronary syndromes.
Subject(s)
Humans , Male , Adult , Middle Aged , Erectile Dysfunction/epidemiology , Endothelium/physiopathology , Acute Coronary Syndrome/etiology , Body Mass Index , Case-Control Studies , Cross-Sectional Studies , Erectile Dysfunction/physiopathology , Life Style , Biomarkers , Probability , Risk Assessment , Risk Factors , Severity of Illness Index , Waist-Hip RatioABSTRACT
Trend in Tuberculosis (TB) rates and association of factors affecting the outcome of this disease were assessed in the Health Service of Viña del Mar-Quillota, Chile from 1999 to 2008. Study of 1291 TB patients by the years 1999 to 2008. We evaluated incidence and mortality rate per 100,000 inhabitants, pulmonary / extrapulmonary ratio, presence of HIV, death and site of infection. It was found a decreasing trend in the incidence rate (p < 0.001 R² = 0.97) and association between the presence of HIV and case fatality rate (p < 0.001). It was not found association between site of disease and mortality rate (p = 0.3) nor a decreasing trend in mortality (p = 0.116) and pulmonary/extrapulmonary ratio (p = 0.194). There is a decreasing trend in the incidence rate of TB patients which reflects a well-functioning system of control and surveillance; the presence of HIV is associated with death because of this it should be considered in clinical management of TB.
Se evalúa la tendencia de las tasas de incidencia de tuberculosis (TBC) y de factores asociados al desenlace de esta enfermedad, en el Servicio de Salud Viña del Mar-Quillota durante los años 1999 2008. Estudio de 1.291 pacientes con TBC entre los años 1999-2008. Se evalúa tasa de incidencia y mortalidad por 100.000 habitantes, razón de casos pulmonares/extrapulmonares, presencia de VIH, tasa de letalidad y localización de la infección. Se observa una tendencia decreciente en la tasa de incidencia (p <0,001; R² = 0,97) y asociación entre presencia de VIH y fallecer (p < 0,001). No se observa asociación entre localización de la enfermedad y fallecimiento (p = 0,3), ni tendencia decreciente en la tasa de mortalidad (p = 0,116) ni en la razón de casos pulmonares/extrapulmonares (p = 0,194). La tendencia decreciente de la tasa de incidencia de TBC refleja un buen funcionamiento del sistema de control y vigilancia. La infección por VIH se asocia con mayor riesgo de muerte por lo que debe considerarse en el enfrentamiento clínico de la TBC.